Drug target
Presynaptic glutamate release (voltage-gated Na+ channels)
Voltage-gated sodium channels / presynaptic glutamate release machinery
1 compound in the CNS pipeline acts on Presynaptic glutamate release (voltage-gated Na+ channels).
Compounds targeting Presynaptic glutamate release (voltage-gated Na+ channels)
| Compound | Action | Affinity | Lead program | Developer |
|---|---|---|---|---|
| Troriluzole (BHV-4157)Small molecule | Inhibitor | — | DiscontinuedObsessive-compulsive disorder | Biohaven Ltd. |