Drug target · DRD5
D5
Dopamine D5 receptor
3 compounds in the CNS pipeline act on D5.
Compounds targeting D5
| Compound | Action | Affinity | Lead program | Developer |
|---|---|---|---|---|
| EcopipamSmall molecule | Antagonist | pKi 8.3 | Filed (NDA)Tourette syndrome | Emalex Biosciences Inc. |
| TavapadonSmall molecule | Partial agonist | Ki 13 nM | Filed (NDA)Parkinson's disease | Cerevel Therapeutics |
| PF-06412562 (CVL-562)Small molecule | Partial agonist | — | Phase 2Schizophrenia | Pfizer Inc. |