Drug target · DRD1
D1
Dopamine D1 receptor
3 compounds in the CNS pipeline act on D1.
Compounds targeting D1
| Compound | Action | Affinity | Lead program | Developer |
|---|---|---|---|---|
| EcopipamprimarySmall molecule | Antagonist | pKi 8.3 | Filed (NDA)Tourette syndrome | Emalex Biosciences Inc. |
| TavapadonprimarySmall molecule | Partial agonist | Ki 9 nM | Filed (NDA)Parkinson's disease | Cerevel Therapeutics |
| PF-06412562 (CVL-562)primarySmall molecule | Partial agonist | — | Phase 2Schizophrenia | Pfizer Inc. |