Drug target · TMEM97

sigma-2 receptor

Sigma-2 receptor (TMEM97 / transmembrane protein 97)

1 compound in the CNS pipeline acts on sigma-2 receptor.

Compounds targeting sigma-2 receptor

CompoundActionAffinityLead programDeveloper
Roluperidone (MIN-101)Small moleculeAntagonistKi 7.53 nMPhase 3SchizophreniaMinerva Neurosciences, Inc.