Drug target · PDE1B

PDE1B

Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B

1 compound in the CNS pipeline acts on PDE1B.

Compounds targeting PDE1B

CompoundActionAffinityLead programDeveloper
Lenrispodun (ITI-214)primarySmall moleculeInhibitorKi 380 pMPhase 2Parkinson's diseaseIntra-Cellular Therapies, Inc.