Drug target · PDE1A

PDE1A

Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A

1 compound in the CNS pipeline acts on PDE1A.

Compounds targeting PDE1A

CompoundActionAffinityLead programDeveloper
Lenrispodun (ITI-214)Small moleculeInhibitorKi 34 pMPhase 2Parkinson's diseaseIntra-Cellular Therapies, Inc.