Drug target · PDE10A

PDE10A

cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

1 compound in the CNS pipeline acts on PDE10A.

Compounds targeting PDE10A

CompoundActionAffinityLead programDeveloper
Elpipodect (MK-8189)primarySmall moleculeInhibitorKi 0.029 nMDiscontinuedSchizophreniaMerck & Co., Inc.