Drug target · NR2E1

TLX

Nuclear receptor TLX (tailless homolog, NR2E1)

1 compound in the CNS pipeline acts on TLX.

Compounds targeting TLX

CompoundActionAffinityLead programDeveloper
ALTO-100 (amdiglurax)primarySmall moleculeAgonistEC50 36.1 pMPhase 2Bipolar depressionAlto Neuroscience, Inc.