Drug target · OPRM1

mu-opioid receptor

mu-type opioid receptor (MOP)

1 compound in the CNS pipeline acts on mu-opioid receptor.

Compounds targeting mu-opioid receptor

CompoundActionAffinityLead programDeveloper
LYBALVI (olanzapine/samidorphan)Small moleculeAntagonistKi 0.05 nMPhase 3SchizophreniaAlkermes plc