Drug target · MTNR1B

MT2

Melatonin receptor 1B

1 compound in the CNS pipeline acts on MT2.

Compounds targeting MT2

CompoundActionAffinityLead programDeveloper
ALTO-300 (agomelatine)Small moleculeAgonistKi 0.12 nMPhase 2Major depressive disorderAlto Neuroscience, Inc.