Drug target
Lysine-gingipain (Kgp)
Lysine-specific gingipain, a cysteine protease virulence factor of Porphyromonas gingivalis
1 compound in the CNS pipeline acts on Lysine-gingipain (Kgp).
Compounds targeting Lysine-gingipain (Kgp)
| Compound | Action | Affinity | Lead program | Developer |
|---|---|---|---|---|
| LHP588primarySmall molecule | Inhibitor | — | Phase 2Alzheimer's disease | Cortexyme, Inc. (now Quince Therapeutics, Inc.) |