Drug target · kgp

Kgp

Lysine-specific gingipain (lysine-gingipain, Porphyromonas gingivalis)

1 compound in the CNS pipeline acts on Kgp.

Compounds targeting Kgp

CompoundActionAffinityLead programDeveloper
Atuzaginstat (COR388)primarySmall moleculeInhibitorDiscontinuedAlzheimer's diseaseCortexyme, Inc. (now Quince Therapeutics, Inc.)