Drug target · KCNQ2

Kv7.2

Potassium voltage-gated channel subfamily Q member 2

2 compounds in the CNS pipeline act on Kv7.2.

Compounds targeting Kv7.2

CompoundActionAffinityLead programDeveloper
Azetukalner (XEN1101)primarySmall moleculeActivatorEC50 27 nMPhase 3EpilepsyXenon Pharmaceuticals Inc.
Opakalim (BHV-7000)primarySmall moleculeActivatorEC50 0.6 µMPhase 3EpilepsyBiohaven Ltd.