Drug target · OPRK1
kappa-opioid receptor
kappa-type opioid receptor (KOP)
1 compound in the CNS pipeline acts on kappa-opioid receptor.
Compounds targeting kappa-opioid receptor
| Compound | Action | Affinity | Lead program | Developer |
|---|---|---|---|---|
| LYBALVI (olanzapine/samidorphan)Small molecule | Partial agonist | Ki 0.23 nM | Phase 3Schizophrenia | Alkermes plc |