Drug target · HTR7

5-HT7

5-hydroxytryptamine receptor 7

2 compounds in the CNS pipeline act on 5-HT7.

Compounds targeting 5-HT7

CompoundActionAffinityLead programDeveloper
Brilaroxazine (RP5063)Small moleculeAntagonistKi 2.7 nMPhase 3SchizophreniaReviva Pharmaceuticals Holdings, Inc.
LB-102 (N-methylamisulpride)Small moleculeAntagonistKi 31 nMPhase 3SchizophreniaLB Pharmaceuticals Inc.