Drug target · HRH3
H3 receptor
Histamine H3 receptor
2 compounds in the CNS pipeline act on H3 receptor.
Compounds targeting H3 receptor
| Compound | Action | Affinity | Lead program | Developer |
|---|---|---|---|---|
| ALTO-203primarySmall molecule | Inverse agonist | — | Phase 2Major depressive disorder | Alto Neuroscience, Inc. |
| Enerisant (TS-091)primarySmall molecule | Inverse agonist | pKi 8.8 | DiscontinuedNarcolepsy | Taisho Pharmaceutical Co., Ltd. |