Drug target · HRH1
H1 receptor
Histamine H1 receptor
2 compounds in the CNS pipeline act on H1 receptor.
Compounds targeting H1 receptor
| Compound | Action | Affinity | Lead program | Developer |
|---|---|---|---|---|
| TNX-102 SL (cyclobenzaprine HCl sublingual)primarySmall molecule | Antagonist | Ki 1.3 nM | ApprovedFibromyalgia | Tonix Pharmaceuticals Holding Corp. |
| Olanzapine extended-release injectable suspension (TEV-'749)Small molecule | Antagonist | — | Filed (NDA)Schizophrenia | Teva Pharmaceutical Industries Ltd. |