Drug target · HCRTR1

OX1R

Orexin receptor type 1 (OX1)

1 compound in the CNS pipeline acts on OX1R.

Compounds targeting OX1R

CompoundActionAffinityLead programDeveloper
Vornorexant (TS-142)Small moleculeAntagonistIC50 1.61 nMApprovedInsomniaTaisho Pharmaceutical Co., Ltd.