Drug target · GRM2

mGlu2

Metabotropic glutamate receptor 2

1 compound in the CNS pipeline acts on mGlu2.

Compounds targeting mGlu2

CompoundActionAffinityLead programDeveloper
TS-161primarySmall moleculeAntagonistKi 4.27 nMDiscontinuedTreatment-resistant depressionTaisho Pharmaceutical Co., Ltd.