Drug target · GRIN2D
GluN2D
Glutamate ionotropic receptor NMDA type subunit 2D
1 compound in the CNS pipeline acts on GluN2D.
Compounds targeting GluN2D
| Compound | Action | Affinity | Lead program | Developer |
|---|---|---|---|---|
| Esmethadone (REL-1017)primarySmall molecule | Antagonist | IC50 13.5 uM | DiscontinuedMajor depressive disorder | Relmada Therapeutics, Inc. |