Drug target · GABRA5

GABA-A receptor alpha-5

Gamma-aminobutyric acid type A receptor subunit alpha-5

1 compound in the CNS pipeline acts on GABA-A receptor alpha-5.

Compounds targeting GABA-A receptor alpha-5

CompoundActionAffinityLead programDeveloper
Darigabat (CVL-865)Small moleculePAMKi 18 nMDiscontinuedEpilepsyCerevel Therapeutics Holdings, Inc.