Drug target · GABRA2
GABA-A receptor alpha-2
Gamma-aminobutyric acid type A receptor subunit alpha-2
1 compound in the CNS pipeline acts on GABA-A receptor alpha-2.
Compounds targeting GABA-A receptor alpha-2
| Compound | Action | Affinity | Lead program | Developer |
|---|---|---|---|---|
| Darigabat (CVL-865)primarySmall molecule | PAM | Ki 2.9 nM | DiscontinuedEpilepsy | Cerevel Therapeutics Holdings, Inc. |