Drug target · GABRA1
GABA-A receptor alpha-1
Gamma-aminobutyric acid type A receptor subunit alpha-1
1 compound in the CNS pipeline acts on GABA-A receptor alpha-1.
Compounds targeting GABA-A receptor alpha-1
| Compound | Action | Affinity | Lead program | Developer |
|---|---|---|---|---|
| Darigabat (CVL-865)Small molecule | PAM | Ki 0.18 nM | DiscontinuedEpilepsy | Cerevel Therapeutics Holdings, Inc. |