Drug target · AVPR1B

V1B receptor

Arginine vasopressin receptor 1B

2 compounds in the CNS pipeline act on V1B receptor.

Compounds targeting V1B receptor

CompoundActionAffinityLead programDeveloper
Nelivaptan (BH-200)primarySmall moleculeAntagonistPhase 2Major depressive disorderSanofi
Brezivaptan (TS-121 / ANC-501)primarySmall moleculeAntagonistDiscontinuedMajor depressive disorderTaisho Pharmaceutical Co., Ltd.