Drug target · GRIA1

AMPA receptor (GluA1)

Glutamate ionotropic receptor AMPA type subunit 1

1 compound in the CNS pipeline acts on AMPA receptor (GluA1).

Compounds targeting AMPA receptor (GluA1)

CompoundActionAffinityLead programDeveloper
Osavampator (NBI-1065845)primarySmall moleculePAMEC50 2.2 µMPhase 3Major depressive disorderNeurocrine Biosciences, Inc.