Drug target · CHRNA4
alpha4beta2 nAChR
Neuronal nicotinic acetylcholine receptor alpha4beta2 subtype (CHRNA4/CHRNB2 heteropentamer)
1 compound in the CNS pipeline acts on alpha4beta2 nAChR.
Compounds targeting alpha4beta2 nAChR
| Compound | Action | Affinity | Lead program | Developer |
|---|---|---|---|---|
| RopanicantprimarySmall molecule | Antagonist | Ki 1.5 nM | Phase 2Major depressive disorder | Suven Life Sciences Limited |