How many clinical trials are recruiting for schizoaffective disorder?

18 drug-interventional schizoaffective disorder trials are currently recruiting participants, out of 326 registered interventional trials.

Psychotic Disorders

Schizoaffective disorder drug pipeline

ICD-11 6A21
MeSH D011618

Compounds in development

No compounds populated for this indication yet — see registered trials below.

Trials recruiting now (18)

18 drug-interventional schizoaffective disorder trials recruiting now, of 326 registered interventional trials. Browse all on ClinicalTrials.gov →

Phase 4Clinical Trial of an IL-23 Inhibitor for Immune Activation in Clinical Trial of an IL-23 Inhibitor for Immune Activation in People With Schizophrenia
Placebo, IL-23
University of Maryland, Baltimoren=40United States · 1 siteStarted Sep 2026NCT07615075
Phase 4Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder
semaglutide, Phentermine-Topiramate, naltrexone and bupropion (combination)
Mayo Clinicn=100United States · 1 siteStarted Jan 2026NCT07213466
Phase 4A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor
Valbenazine
Neurocrine Biosciences, Inc.n=50United States · 22 sitesStarted Aug 2025NCT07105111
Phase 4Exercise and Olanzapine-samidorphan
Olanzapine-samidorphan + exercise
New York State Psychiatric Instituten=30United States · 1 siteStarted Jun 2025NCT06740890
Phase 4Anticholinergic Deprescription in Schizophrenia
Anticholinergic Deprescription, No Anticholinergic Deprescription
Deepak K. Sarpal, M.D.n=105United States · 1 siteStarted Feb 2025NCT06562608
Phase 4Metabolic Effects of Adjunctive Lumateperone Treatment in Clozapine-Treated Patients With Schizophrenia
Lumateperone, Placebo
University of Massachusetts, Worcestern=50United States · 1 siteStarted Apr 2024NCT06174116
Phase 4Clozapine for the Prevention of Violence in Schizophrenia: a Randomized Clinical Trial
Clozapine, treatment as usual
New York State Psychiatric Instituten=280United States · 7 sitesStarted Mar 2022NCT05208190
Phase 4CLOZAPINE Response in Biotype-1
clozapine, risperidone
University of Texas Southwestern Medical Centern=524United States · 5 sitesStarted Mar 2022NCT04580134
Phase 4Bazedoxifene -Treatment for Women With Schizophrenia
Bazedoxifene Acetate, Placebo
The Alfredn=160Australia · 1 siteStarted Oct 2019NCT04113993
Phase 4Smoking Cessation With Varenicline in Schizophrenia: Antipsychotic-Induced Neurological Symptoms as Correlates
Varenicline
Corporal Michael J. Crescenz VA Medical Centern=10United States · 1 siteStarted Jan 2019NCT03495024
Phase 4Switching From Twice-Daily to Once-Daily Clozapine Dosing in Schizophrenia
Clozapine
Centre for Addiction and Mental Healthn=30Canada · 1 siteStarted Aug 2016NCT02639702
Phase 3Cognitive Strategies in Early Psychosis 2
Modafinil, D-serine solution, Placebo
University of Minnesotan=24Started Jul 2026NCT07263022

Showing the 12 most advanced of 18 recruiting drug trials · see all on ClinicalTrials.gov →

Frequently asked

How many clinical trials are recruiting for schizoaffective disorder?: 18 drug-interventional schizoaffective disorder trials are currently recruiting participants, out of 326 registered interventional trials.