What are the next anorexia nervosa trial readouts?

Upcoming catalysts include Psilocybin (COMP360) (after primary completion (Nov 2024)).

How many clinical trials are recruiting for anorexia nervosa?

12 drug-interventional anorexia nervosa trials are currently recruiting participants, out of 63 registered interventional trials.

Eating Disorders

Anorexia nervosa drug pipeline

ICD-11 6B80
MeSH D000856

1 compound from 1 company is in active clinical development for anorexia nervosa.

1Compound

1Company

0Phase 3+

1Upcoming readout

14Trials recruiting

Phase 2 1

Mechanisms: Psychedelic (1)

Pipeline data compiled July 2026 · every fact sourced.

Upcoming readouts & recent results

after primary completion (Nov 2024)DelayedPsilocybin (COMP360)Topline dataNCT05481736
Phase 2 anorexia nervosa proof-of-concept (NCT05481736) completed Nov 2024; topline EDE result not yet disclosed. ↗

See the full catalyst calendar →

Compounds in development (1)

Compound	Company	Phase	Status	Mechanism
Psilocybin (COMP360)	COMPASS Pathways plc	Phase 2	Completed	5-HT2A Partial agonist

Trials recruiting now (12)

12 drug-interventional anorexia nervosa trials recruiting now, of 63 registered interventional trials. Browse all on ClinicalTrials.gov →

Phase 3Pediatric Prolonged-Release Melatonin for Sleep Disturbances in Children and Adolescents With Anorexia Nervosa (MELSom-ANOREXIA)
Pediatric Prolonged-Released Melatonin (PedPRM), Placebo
Assistance Publique Hopitaux De Marseillen=120France · 1 siteStarted Sep 2026NCT07576764
Phase 2An Open Trial of a Novel Pharmacotherapy for Habit Modification in Anorexia Nervosa
Donepezil
New York State Psychiatric Instituten=10United States · 1 siteStarted Jun 2026NCT06518941
Phase 2Safety, Therapeutic Potential, and Mechanisms of Two Psilocybin Doses, Administered With Psychological Support in Young Adults With Anorexia Nervosa
Psilocybin
Region Skanen=40Sweden · 1 siteStarted Apr 2026NCT07169747
Phase 2Ketamine Effects on Learning In Eating Disorders
Ketamine infusion
Amanda Downey, MDn=20United States · 1 siteStarted Jun 2025NCT06736769
Phase 2Study of Psilocybin for Anorexia in Young Adults
Psilocybin
Marissa Raymond-Flesch, MD, MPHn=40United States · 2 sitesStarted Nov 2024NCT06399263
Phase 2Acetylcholinesterase Inhibitor in Anorexia Nervosa: Multicenter, Double-Blind, Placebo-Controlled Trial
Donepezil 2.5 mg, Donepezil 5 mg, Placebo Comparator
Centre Hospitalier St Annen=147Started Nov 2024NCT06687993
Phase 2Metreleptin in Anorexia Nervosa
Metreleptin, Sodium chloride
Gabriella Milosn=50Switzerland · 1 siteStarted May 2024NCT06305182
Phase 2Comparing Olanzapine and Mirtazapine in the Improvement of Unintentional Weight Loss for Patients with Advanced Stage Cancer
Mirtazapine, Olanzapine
Englewood Hospital and Medical Centern=170United States · 1 siteStarted Jan 2022NCT05170919
Phase 2Transdermal Estrogen in Women With Anorexia Nervosa
Transdermal estrogen, Placebos
Pouneh K. Fazeli, MDn=66United States · 1 siteStarted Aug 2020NCT03875378
Phase 0Naltrexone Neuroimaging in Teens With Eating Disorders
Naltrexone, Placebo
Children's Mercy Hospital Kansas Cityn=60United States · 1 siteStarted Sep 2022NCT05509257
UnknownFecal Microbiota Transplant for Anorexia Nervosa
Fecal Microbiota Transplant, Placebo
Hamilton Health Sciences Corporationn=20Started Jun 2026NCT06593366
UnknownA Study on the Effects of Combined FMT on Gut Microbiota and Eating Disorder Symptoms in AN
Fecal Microbiota Transplantation, Placebo
Shanghai Mental Health Centern=30Started Sep 2025NCT06744751

Frequently asked

How many drugs are in development for anorexia nervosa?: 1 compound from 1 company is in active clinical development for anorexia nervosa.
What are the next anorexia nervosa trial readouts?: Upcoming catalysts include Psilocybin (COMP360) (after primary completion (Nov 2024)).
How many clinical trials are recruiting for anorexia nervosa?: 12 drug-interventional anorexia nervosa trials are currently recruiting participants, out of 63 registered interventional trials.