2026 ECNP Congress

EP01-1028

Artificial intelligence in suicide risk prediction: clinical applicability and ethical considerations

Emiliya Dimitrova-Ilieva — P. Chumpalova-Tumbeva, G. Dogancali Yanchev · Medical University - Pleven, Psychiatry and Medical psychology, Pleven, Bulgaria

Introduction

Suicide represents a serious global challenge. Widely recognized clinical methods for suicide risk assessment demonstrate limited predictive value, particularly for short-term risk. These methods are primarily based on clinical judgment, risk factors, and standardized scales. In recent years, with the development and advancement of artificial intelligence (AI), new methodologies have been introduced for identifying individuals at increased risk of suicidal behavior. AI enables the analysis of multimodal datasets, such as health records, clinical assessments, and digital behavioral data, with the aim of identifying complex, nonlinear patterns associated with suicidal behavior. Systematic reviews and meta-analyses indicate that machine learning (ML) models can outperform conventional statistical and clinical methods in certain cases, offering improved sensitivity in detecting individuals at elevated risk of suicide.

Aim

The present study aims to examine the clinical applicability of AI-based models for predicting suicide risk and to evaluate the associated ethical and practical considerations in psychiatric practice.

Methods

A review of current scientific literature was conducted. The focus is on studies and meta-analyses that use machine learning (ML) algorithms applied to various available data sources, including electronic health records, behavioral data, clinical assessments, and emerging sources such as digital phenotyping. Emphasis is placed on model performance, generalizability, and potential for clinical integration.

Results

AI-based models for predicting suicidal behavior demonstrate moderate to high accuracy in identifying individuals at increased risk of suicide, often outperforming traditional methods in terms of sensitivity. The integration of diverse data sources enhances predictive capability. However, the clinical applicability of AI-based suicide prediction remains limited by several methodological and practical challenges. Due to heterogeneity in the data used - such as outcome definitions and validation strategies, model performance is often inconsistent. Many models lack external validation and real-world testing, raising concerns about their generalizability and applicability in clinical practice. Additionally, high rates of false-positive results may lead to unnecessary interventions, increased burden on patients, and strain on healthcare systems.

Discussion

Although AI-based prediction of suicidal behavior offers promising complementary tools for suicide risk assessment, it should not be considered a substitute for comprehensive clinical evaluation. Their integration into psychiatric practice raises significant ethical concerns. Key challenges include data privacy and informed consent, particularly when using sensitive psychiatric or digital information, as well as algorithmic bias, which may exacerbate existing health inequalities. Issues of professional responsibility must also be considered - specifically, who is accountable for decisions based on algorithmic predictions, and how to balance patient autonomy with the duty to intervene in cases of high risk.

Conclusion

Artificial intelligence (AI) holds significant potential to complement existing strategies and tools for the prevention of suicidal behavior. However, before widespread implementation in routine clinical practice, further validation, standardization, and the development of robust ethical frameworks are required, along with assessments of fairness and interdisciplinary collaboration to ensure that these technologies are both effective and aligned with patient-centered care.

References

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