TRANSCRANIAL MAGNETIC STIMULATION: DURABILITY OF ANTI-DEPRESSANT RESPONSE

This presentation will summarize a review of the literature outlining the long-term durability of the antidepressant effects of transcranial magnetic stimulation(TMS). Durability data out to 12 months will be discuss for standard TMS protocols. Strategies for relapse prevention including preservation/maintenance TMS and psychopharmacology will be discussed. Additionally, the current level of evidence for the durability of accelerated TMS protocols will be reviewed. The proposed talk will provide a necessary overview of TMS durability and allow for the learner to compare and contrast with other interventions for treatment resistant depression. The talk updates the state of the field for evidence based relapse prevention strategies.

References

Noda, Y., Wada, M., Mimura, Y., Taniguchi, K., Tarumi, R., Moriyama, S., … and Nakajima, S. Repetitive Transcranial Magnetic Stimulation as Maintenance Treatment of Depression: The MAINT-R Randomized Clinical Trial. JAMA Network Open. 2025; 8(6), e2515881-e2515881. Matsuda, Y., Sakuma, K., Kishi, T., Esaki, K., Kito, S., Shigeta, M., and Iwata, N. Repetitive transcranial magnetic stimulation for preventing relapse in antidepressant treatment-resistant depression: A systematic review and meta-analysis of randomized controlled trials. Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation. 2023; 16(2), 458-461. Wilson, S., Croarkin, P. E., Aaronson, S. T., Carpenter, L. L., Cochran, M., Stultz, D. J., and Kozel, F. A. Systematic review of preservation TMS that includes continuation, maintenance, relapse-prevention, and rescue TMS. Journal of Affective Disorders. 2022; 296, 79-88.